Pyelonephritis and Hypertension

The work of Goldblatt 1 has shown that hypertension can be experimentally produced in animals by decreasing or altering the blood supply to the kidneys. Soon after the announcement of his experiments there began to appear in the literature clinical counterparts of his work. Mullholland 2 reviewed the literature in this regard and classified the reported cases of hypertension resulting from interference with the blood flow through the kidneys in the following manner: Intrinsic, infection within the kidney Bilateral, resulting from Benign obstruction of the prostate Partial obstruction of the ureters Accompanying condition in the bladder causing clinical pyelonephritis Stone Diverticulum Malignant growth Bilateral infection Unilateral, resulting from Pyelonephritis Calculi Contracted kidney caused by Trauma Infection Tuberculosis of kidney Extrinsic, effecting interference with the circulation in the renal artery Unilateral Malposition Abnormal course and position of artery Atheromatous plaques Infarct of the kidney Thrombosis with recanalization Hydronephrosis with pressure on artery