Primary renal angiosarcoma is a rare entity whose diagnosis relies on specific morphological and immunohistochemical features.
Confirms IHC panel utility for rare primary renal angiosarcoma diagnosis; leaves open optimal therapy and outcomes data.
Kidney angiosarcomas usually metastasize from the skin, soft tissue, or visceral primary lesions, whereas primary renal angiosarcomas are rare. We report a case of primary renal angiosarcoma with morphological features similar to those of anastomosis hemangioma. Microscopically, there were multiple irregular anastomosing vascular spaces or channel‐like labyrinthine structures, and the tumor cells were positive for CD31, CD34, FLI‐1, PAX8, and vimentin; focally positive for factor VIII, CD10, and Ki‐67 (approximately 5%); and uniformly‐negative for CK, S‐100, and Melan‐A. The diagnosis of angiosarcoma depends on morphological and immunohistochemical examinations.
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Li et al. (2018) studied this question.
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