Why the study?
Does increased sodium chloride excretion (natriuresis) protect against glycerol-induced acute myohemoglobinuric renal failure in rats independently of renal cortical renin content depletion?
Does increased sodium chloride excretion (natriuresis) protect against glycerol-induced acute myohemoglobinuric renal failure in rats independently of renal cortical renin content depletion?
Natriuresis, rather than renal cortical renin content depletion, appears to protect against glycerol-induced acute myohemoglobinuric renal failure in rats.
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Natriuresis may protect against glycerol-induced renal failure in rats independently of RCRC; hypothesis-generating for human AKI, not yet practice-changing.
Bidani et al. (2008) studied this question.
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