Highlights the critical need to investigate patients with multiple blue naevi or lentigines for potentially life-threatening cardiac myxomas associated with Carney complex.
May prompt Carney complex evaluation after embolic events in patients with multiple naevi; single case leaves open systematic screening studies.
Carney complex is characterized by spotty pigmentation (blue naevi and lentigines), myxomas (cardiac, cutaneous, mammary), endocrine over-activity (Cushing's syndrome, acromegaly), testicular tumours, and schwannomas. We report a male with multiple blue naevi, lentigines, testicular large cell calcifying Sertoli-cell tumour and four cardiac myxomas. The myxomas caused two cerebrovascular accidents and a myocardial infarction. All patients with multiple blue naevi or lentigines should be investigated for the life-threatening association of cardiac myxomas.
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Bleasel et al. (1999) studied this question.
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