What question did this study set out to answer?

To characterize the hematologic manifestations of hemoglobin E trait and improve clinical recognition of this benign condition.

January 1, 1979BloodOpen Access

Hemoglobin E trait reexamined: a cause of microcytosis and erythrocytosis

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To characterize the hematologic manifestations of hemoglobin E trait and improve clinical recognition of this benign condition.
Evaluated hematologic parameters in 21 individuals with hemoglobin E trait (N=21).
Included individuals of Tai-dam, Vietnamese, Chinese, Laotian, and European ancestry.
Demonstrated uniform hematologic manifestations across subjects, characterized by slight microcytosis and red blood cell morphology resembling thalassemia minor.
Identified frequently elevated erythrocyte counts along with confirmed hemoglobin instability.

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Implication

Observational evaluation reveals consistent microcytosis, erythrocytosis, and hemoglobin instability in individuals with hemoglobin E trait, highlighting its resemblance to thalassemia minor.

Cite This Study

Vf et al. (1979) studied this question.

synapsesocial.com/papers/6a8a50f91e528df4f2ec711b https://doi.org/10.1182/blood.v53.1.109.109

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Implication

Observational evaluation reveals consistent microcytosis, erythrocytosis, and hemoglobin instability in individuals with hemoglobin E trait, highlighting its resemblance to thalassemia minor.

Hemoglobin E trait reexamined: a cause of microcytosis and erythrocytosis

Key Points

Discussion

Implication

Cite This Study

Hemoglobin E trait reexamined: a cause of microcytosis and erythrocytosis

Key Points

Discussion

Implication

Cite This Study

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