Why the study?
Does major depressive disorder involve abnormal respiratory sinus arrhythmia (RSA) fluctuation compared to healthy controls?
Does major depressive disorder involve abnormal respiratory sinus arrhythmia (RSA) fluctuation compared to healthy controls?
Major depressive disorder is associated with deficits in cardiac vagal control, specifically reduced respiratory sinus arrhythmia fluctuation and a lack of task-related vagal suppression.
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MDD may involve impaired vagal regulation; case-control data leave open causality and any clinical role for RSA monitoring.
Rottenberg et al. (2007) studied this question.
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