Population
Rat in vitro aortic arch-aortic nerve preparations (single fibre baroreceptors)
Design
Preclinical
Authors
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May caution against TTX-only models of baroreceptor inhibition; leaves open non-sodium channel mechanisms in animal preparations.
The contrasting effects of local anesthetics and TTX on baroreceptor discharge suggest mechanisms beyond simple TTX-sensitive sodium channel blockade.
Andresen et al. (1994) studied this question.
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