Population
Alternatively activated macrophages (Mphi2)
Design
Preclinical
Authors
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Antagonistic IL-4/glucocorticoid effects in murine macrophages should not yet change practice; leaves open translation to human ECM remodeling and phagocytosis.
IL-4 and dexamethasone exert antagonistic effects on extracellular matrix remodeling and phagocytosis in type-2 macrophages, highlighting the heterogeneity of alternative macrophage activation.
Gratchev et al. (2005) studied this question.
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