Why the study?
Sydenham chorea can occur as the sole clinical feature of ARF, masking subclinical carditis that can progress to chronic RHD if missed.
Sydenham chorea can present as an isolated sign of acute rheumatic fever, underscoring the importance of routine echocardiographic screening to detect subclinical carditis and prevent chronic rheumatic heart disease.
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Echocardiography may detect subclinical carditis in isolated Sydenham's chorea; leaves open whether screening changes ARF outcomes.
Mohod et al. (2025) studied this question.
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