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January 1, 1978The Annals of StatisticsOpen Access

Maximum Likelihood Estimation of Dose-Response Functions Subject to Absolutely Monotonic Constraints

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HGH. A. GuessUniversity of North Carolina at Chapel HillKCKenny S. CrumpUniversity of California, Riverside

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Guess et al. (1978) studied this question.

synapsesocial.com/papers/6a8a613a754a5a619a723848https://doi.org/10.1214/aos/1176344069
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  1. 1Confidence Intervals and Test of Hypotheses Concerning Dose Response Relations Inferred from Animal Carcinogenicity Data1977 · 119 citations