Population
A patient with severe, progressive esophagitis and herpes simplex virus isolates, along with an encephalitis…
Design
Case_report
Authors
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May indicate retained virulence in acyclovir-resistant HSV; hypothesis-generating case report challenging assumptions of attenuation.
Acyclovir-resistant herpes simplex can maintain pathogenicity and cause progressive clinical disease, challenging the notion that resistance always attenuates virulence.
Stephen L. Sacks (1989) studied this question.
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