Population
Six mechanically ventilated pigs anaesthetized with propofol and fentanyl
Design
Preclinical
Authors
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Local cortical autoregulatory heterogeneity in animals cautions against uniform assumptions; leaves open relevance to human regional ischemia.
This study demonstrates that while global cerebral blood flow exhibits classic autoregulation, local cortical blood flow autoregulatory capacity is heterogeneous and lacking in some areas.
Kimme et al. (2002) studied this question.
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