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HeLa cells, replicating cell cultures, and mouse models with specific knock-out and knock-in modifications…
Design
Review
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No general model of measles persistence can be derived; leaves open the need for reverse genetics and mouse models to advance understanding.
This review highlights the current understanding of measles virus persistence mechanisms and specific mutations associated with CNS infection, emphasizing the need for reverse genetics and mouse models to further knowledge.
Robert Rustigian (1962) studied this question.
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