Morphometry and strain distribution of the C57BL/6 mouse aorta

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Population

5 C57BL/6 mice

Design

Preclinical

Authors

Discussion

Provides reference aortic strain data in mice; leaves open translation to human disease models.

Population

5 C57BL/6 mice

Intervention

Imaging with a 13-MHz ultrasound probe and casting of aortas

Outcome

Variations of morphometry (diameter, wall thickness, and curvature), strain, and stress of the mouse aortasurrogate

This study provides baseline morphometric and strain data for the normal C57BL/6 mouse aorta, serving as a reference for future disease models.

Guo et al. (2002) studied this question.

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