What question did this study set out to answer?

To assess clinical and pathologic factors associated with survival in lymphoblastic lymphoma across diverse patient age groups.

December 1, 1981Cancer

Lymphoblastic lymphoma: A clinicopathologic study of 95 patients

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Authors

BNBharat N. NathwaniCity Of Hope National Medical Center LDLawrence W. DiamondCity Of Hope National Medical Center CWCarl D. WinbergUniversity of Southern California

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Implication

Retrospective clinicopathologic study reveals distinct age-related features in lymphoblastic lymphoma patients, suggesting a different biologic behavior in older individuals.

Key Points

To assess clinical and pathologic factors associated with survival in lymphoblastic lymphoma across diverse patient age groups.
Retrospective review of N=95 patients (aged 4 to 84 years, median 30; 68 male, 27 female) identified through the Repository Center for Lymphoma Clinical Studies.
Patients received treatment under various National Cancer Institute-sponsored Cooperative Oncology group protocols.
Univariate and multivariate statistical analyses evaluated the prognostic impact of clinical features and tumor morphology on overall survival.
Median overall survival across the entire cohort was 17 months (range: 1 to 100 months), and mediastinal masses occurred in 40 patients (75% male).
Patients older than 30 years had significantly lower rates of mediastinal involvement (P = 0.01), fewer mitotic figures (P = 0.04), and reduced progression to leukemia (P = 0.02) compared to patients younger than 30.

Cite This Study

Nathwani et al. (1981) studied this question.

synapsesocial.com/papers/6a8a7067336687a3262e58b6 https://doi.org/10.1002/1097-0142(19811201)48:11<2347::aid-cncr2820481102>3.0.co;2-x

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Implication

Retrospective clinicopathologic study reveals distinct age-related features in lymphoblastic lymphoma patients, suggesting a different biologic behavior in older individuals.

Lymphoblastic lymphoma: A clinicopathologic study of 95 patients

Discussion

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Implication

Key Points

Cite This Study

Lymphoblastic lymphoma: A clinicopathologic study of 95 patients

Discussion

Member takes

Implication

Key Points

Cite This Study

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