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July 29, 2005Journal of Biomechanical EngineeringOpen Access

Quantifying Effects of Plaque Structure and Material Properties on Stress Distributions in Human Atherosclerotic Plaques Using 3D FSI Models

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Population

MRI-based three-dimensional unsteady models for human atherosclerotic plaques

Design

Other

Authors

DTDalin TangWorcester Polytechnic Institute CYChun YangJiangnan University JZJie ZhengMallinckrodt (United States)

Discussion

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Implication

May aid computational plaque vulnerability assessment; leaves open prospective clinical validation of stress metrics.

Structured PICO

P

Population

MRI-based three-dimensional unsteady models for human atherosclerotic plaques

I

Intervention

Computational mechanical analysis using 3D fluid-structure interaction (FSI) models

O

Outcome

Stress and strain distributions in the plaquesurrogate

Computational mechanical analysis using 3D FSI models can quantify stress and strain distributions in atherosclerotic plaques, potentially improving the accuracy of plaque vulnerability assessment.

Cite This Study

Tang et al. (2005) studied this question.

synapsesocial.com/papers/6a8a710f1e528df4f2ec737f https://doi.org/10.1115/1.2073668

Topics

Coronary artery disease Coronary CT angiography

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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

1A method for in-vivo analysis for regional arterial wall material property alterations with atherosclerosis: preliminary results2003 · 42 citations
2Numerical study of blood flow in an anatomically realistic aorto-iliac bifurcation generated from MRI data2000 · 82 citations
3Mechanical Analysis of Heterogeneous, Atherosclerotic Human Aorta1998 · 73 citations
4From Vulnerable Plaque to Vulnerable Patient2003 · 2,278 citations