Why the study?
Does low-level paraplegia alter the low-frequency oscillation in heart rate and blood pressure compared to able-bodied controls?
Population
33 subjects with spinal cord lesions between the fifth thoracic and the fourth lumbar vertebra, and 33…
Comparison
Physiological assessment during supine rest… vs Able-bodied controls undergoing the same…
Design
Case-control
Authors
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Reduced baroreflex effectiveness in paraplegics warrants cautious autonomic assessment; supports resonance origin of 0.1-Hz oscillations but leaves mechanism and clinical impact open.
Does low-level paraplegia alter the low-frequency oscillation in heart rate and blood pressure compared to able-bodied controls?
The absence of 0.1-Hz oscillations in heart rate and blood pressure in paraplegic patients suggests these oscillations are generated by baroreflex resonance rather than a central neural oscillator.
Castiglioni et al. (2006) studied this question.
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