Self-assembly of carcerand-like dimers of calix[4]resorcinarene facilitated by hydrogen bonded solvent bridges

In the presence of solvent molecules which can act simultaneously as hydrogen bond donors and acceptors, the calix[4] resorcinarene 1 can self-assemble into a dimeric carcerand-like complex utilizing an intricate array of hydrogen bonds with the solvent such that pairs of concave molecules associate indirectly in a rim-to-rim fashion to form a relatively large supramolecular cavity.