Why the study?
Does Hextend improve outcomes compared to 6% hetastarch in saline in patients undergoing major surgery with hypovolemia?
Population
120 patients undergoing major surgery requiring treatment for hypovolemia
Comparison
Hextend vs 6% hetastarch in saline (HES)
Design
RCT, randomized
Authors
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Hextend supports use as effective HES alternative in major surgery with lower calcium needs; extends RCT evidence on coagulation safety.
Does Hextend improve outcomes compared to 6% hetastarch in saline in patients undergoing major surgery with hypovolemia?
Hextend is an effective and safe alternative to 6% hetastarch in saline for volume expansion during major surgery, with potential benefits in calcium homeostasis and coagulation.
Gan et al. (1999) studied this question.
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