Why the study?
To determine the frequency of autonomic cardiovascular dysfunction in patients with decompensated cirrhosis.
A high frequency (72.7%) of autonomic cardiovascular dysfunction was observed in patients with decompensated chronic liver disease.
May warrant autonomic screening in decompensated cirrhosis; leaves open prognostic value and intervention needs.
Objective: To determine the frequency of autonomic cardiovascular dysfunction in patents with decompensated cirrhosis. Methodology: This cross-sectional study was conducted from august 2018 to January 2019 at department of medicine, Abbassi Shaheed hospital. A total of 187 diagnosed patients of decompensated chronic liver disease were consecutively included. Lying and standing BP were taken for orthostatic hypotension while 1 minute ECG was recorded for decrease in HRV during breathing. Results: Out of 187, 72.7% had autonomic cardiovascular dysfunction. Conclusion: Almost two thirds of cirrhotic were found to have hemodynamic alterations. Treatment is largely supportive and empiric. Further studies are needed to recognize the burden of autonomic dysfunction.
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Siddiqui et al. (2020) studied this question.
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