Pedigrees with diabetes insipidus, diabetes mellitus, and optic atrophy.

of the occurrences of all of these disorders within a single pedigree. In each of the families identified in the literature and in the present family all 3 manifestations were observed, though not necessarily in the same individual. The as- sembled data permit speculation concerning possibilities that the diabetes insipidus, diabetes mellitus, and optic atrophy in such a kindred represent manifestations of a single genetic trait.