Circulating adiponectin levels correlate negatively with visceral fat area, but not BMI or subcutaneous fat, in obese subjects, suggesting hypoadiponectinemia reflects adipose tissue dysfunction.
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May flag visceral adiposity-related hypoadiponectinemia missed by BMI in obese adults; hypothesis-generating and requires prospective validation before clinical use.
Kishida et al. (2011) studied this question.
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