Why the study?
Does short-term prednisone therapy improve left ventricular systolic function, LV mass, and motor power in patients with muscular dystrophies?
Population
n=25 patients with muscular dystrophy, including 17 cases of Duchenne muscular dystrophy, 3 cases of Becker…
Comparison
Prednisone 5 mg/kg per day on 2 consecutive days… vs Baseline (before therapy)
Design
Case_series
Follow-up
3 months
Authors
Loading...
Hypothesis-generating for prednisone in muscular dystrophy; should not change practice without randomized trials.
Does short-term prednisone therapy improve left ventricular systolic function, LV mass, and motor power in patients with muscular dystrophies?
Three months of intermittent prednisone therapy improved cardiac systolic function and skeletal muscle function in patients with muscular dystrophies.
Mansour et al. (2014) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: