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May support adjunct nesiritide in refractory pediatric biventricular failure; leaves open need for randomized trials.
Although nesiritide has been used in adults with left heart failure, the experience in the paediatric population is limited. We reviewed and analysed our experience with continuous nesiritide infusion as adjunct therapy in children with biventricular dysfunction due to diverse aetiologies and suffering from oliguria despite intravenous diuretics and inotropic therapies for heart-failure management.
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Das et al. (2015) studied this question.
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