Why the study?
Does Spirulina prevent doxorubicin-induced cardiotoxicity in a mouse model?
Population
Mouse model of doxorubicin (DOX)-induced cardiotoxicity and in vitro ovarian cancer cells.
Comparison
Spirulina administered orally for 3 days twice… vs Doxorubicin treatment alone.
Design
Preclinical
Follow-up
3 weeks after the end of the doxorubicin treatment period
Authors
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Spirulina shows no immediate clinical role in doxorubicin therapy; leaves open translation of mouse cardioprotection to humans.
Does Spirulina prevent doxorubicin-induced cardiotoxicity in a mouse model?
Spirulina demonstrates cardioprotective effects against doxorubicin-induced toxicity in a mouse model without compromising doxorubicin's anti-tumor efficacy in vitro.
Khan et al. (2005) studied this question.
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