November 1, 1983Neuropediatrics
Epilepsy Presenting as Infantile Autism - Two Case Studies
Why the study?
Does anticonvulsive pharmacological treatment improve psychotic symptoms and EEG changes in patients with infantile autism and underlying epileptogenic EEG changes?
Population
2 cases diagnosed as suffering from infantile autism with underlying epileptogenic changes in the EEG
Design
Case_series
Authors
Discussion
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Member takes
Implication
May warrant anticonvulsant trial in autism with epileptiform EEG and psychosis; hypothesis-generating, requires controlled confirmation.
Structured PICO
Does anticonvulsive pharmacological treatment improve psychotic symptoms and EEG changes in patients with infantile autism and underlying epileptogenic EEG changes?
P
Population
2 cases diagnosed as suffering from infantile autism with underlying epileptogenic changes in the EEG
I
Intervention
Anticonvulsive pharmacological treatment
O
Outcome
Disappearance of psychotic symptoms and pathological EEG changessurrogate
Anticonvulsive therapy may resolve psychotic symptoms and EEG abnormalities in patients presenting with infantile autism who have underlying epileptogenic changes.
Cite This Study
Gillberg et al. (1983) studied this question.