A simple and efficient approach to 6-perfluoroalkylated phenanthridines starting with readily prepared isonitriles and commercially available cheap perfluoroalkyl iodides as perfluoroalkyl radical precursors is described. Various 6-perfluoroalkylated phenanthridines are obtained in moderate to excellent yields. The sequence comprises a perfluoroalkylation with concomitant arene formation.
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Zhang et al. (2014) studied this question.
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