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Many investigators have considered the possible role of asphyxia in sudden infant death syndrome (SIDS). Suggested mechanisms have included those which might mechanically compromise the airway, such as smothering, laryngospasm [1], and nasal obstruction from upper respiratory tract infection in the obligate nasal breathing infant [2]. Much current research focuses on the possibility of centrally mediated respiratory failure related to sleep apnea, functional abnormality of the ponto-medullary respiratory centers [3], chemically induced laryngeal apnea [4], and inappropriate operation of the oxygen-conserving reflex (“diving reflex”) [5].
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Simson et al. (1977) studied this question.
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