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January 1, 2001CancerOpen Access

Adrenocortical carcinoma

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Population

139 patients with adrenocortical carcinoma registered at the University of Texas M.D. Anderson Cancer Center…

Design

Cohort

Follow-up

5 years

Authors

RVRena Vassilopoulou‐SellinPSPamela N. Schultz

Discussion

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Overview

Improved survival in recent cohorts supports evolving care; hypothesis-generating for specific therapies in adrenocortical carcinoma.

Structured PICO

P
Population
139 patients with adrenocortical carcinoma registered at the University of Texas M.D. Anderson Cancer Center since 1980.
C
Comparator
Patients reviewed in earlier reports from the same institution (prior to 1980).
O
Outcome
5-year survival ratehard clinical

Patients with adrenocortical carcinoma diagnosed since 1980 are living longer with a 5-year survival rate of 60%, suggesting improved diagnostic and supportive measures have beneficially impacted the natural history of the disease.

Cite This Study

Vassilopoulou‐Sellin et al. (2001) studied this question.

synapsesocial.com/papers/6a8a9eaab1e5d05ea8ecb0e3https://doi.org/10.1002/1097-0142(20010901)92:5<1113::aid-cncr1428>3.0.co;2-i
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Pathologic Features of Prognostic Significance for Adrenocortical Carcinoma After Curative Resection1999 · 117 citations
  2. 2Impact of adjuvant mitotane on the clinical course of patients with adrenocortical cancer1993 · 127 citations
  3. 3Prevalence of Adrenal Carcinoma Among Incidentally Discovered Adrenal Masses1997 · 144 citations
  4. 4Incidentally Discovered Adrenal Masses*1995 · 833 citations
  5. 5Mitotane associated with etoposide, doxorubicin, and cisplatin in the treatment of advanced adrenocortical carcinoma1998 · 145 citations