Case report reveals hyperpigmented palmoplantar macules following a healed genital chancre in a young adult, highlighting atypical cutaneous manifestations of secondary syphilis.
A 25-year-old man presented to our outpatient department with a complaint of asymptomatic, hyperpigmented, flat lesions over the palms and soles for 5 months.He had no other cutaneous or systemic complaints.Cutaneous examination revealed multiple brownish-black macules of varying sizes, ranging from 1 × 1 cm to 2 × 2 cm, presented over the palms and soles [Figure 1a and b].ere was no lymphadenopathy, generalized rash, or oral mucosal lesions on examination.On detailed history taking, he revealed a history of unprotected sexual intercourse with multiple male and female partners.Genital examination revealed a healed scar over the prepuce of the penis [Figure 1c], suggestive of a previous chancre.
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Nitish Kumar (2026) studied this question.
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