What does this research mean for the field?

Persistent Müllerian duct syndrome (PMDS) in genetically normal (78,XY) male dogs can present with cryptorchidism, persistent Müllerian derivatives, and associated Sertoli cell tumors, necessitating its inclusion in differential diagnoses for cryptorchid dogs with reproductive tract abnormalities. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To describe the clinical presentation, surgical management, histopathology, and cytogenetic findings of persistent Müllerian duct syndrome associated with a Sertoli cell tumor in a male Schnauzer dog.

August 23, 2026PetsOpen Access

Persistent Müllerian Duct Syndrome Associated with a Sertoli Cell Tumor in a Male Schnauzer Dog

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Authors

DEDanna Carolina Arenas EljachInstituto del Corazón de Bucaramanga JNJavier Hernando Albarracin NavasUniversidad Cooperativa de Colombia LRLuz Zoraya Beatriz Duarte RodriguezInstituto del Corazón de Bucaramanga

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Implication

Case report reveals persistent Müllerian duct derivatives and a Sertoli cell tumor in a cryptorchid Schnauzer dog, highlighting the need to evaluate sex development disorders during testicular...

Key Points

To describe the clinical presentation, surgical management, histopathology, and cytogenetic findings of persistent Müllerian duct syndrome associated with a Sertoli cell tumor in a male Schnauzer dog.
Evaluated a 9-year-old male Schnauzer presenting with digestive and urinary signs via abdominal radiography, ultrasonography, and exploratory laparotomy.
Performed histopathological examination on surgically excised gonadal and abnormal reproductive tract tissues.
Conducted cytogenetic analysis using R-replicative banding after bromodeoxyuridine incorporation to characterize the chromosomal karyotype.
Surgical exploration and histopathology revealed cryptorchidism, persistent Müllerian duct derivatives including uterine horn-like structures, severe seminiferous tubular atrophy, and a unilateral Sertoli cell tumor.
Cytogenetic analysis confirmed a normal male karyotype (78,XY) without structural abnormalities or chromosomal mosaicism, diagnosing a 78,XY disorder of sex development.

Cite This Study

Eljach et al. (2026) studied this question.

synapsesocial.com/papers/6a8aadf37677a341144467da https://doi.org/10.3390/pets3030037

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Implication

Case report reveals persistent Müllerian duct derivatives and a Sertoli cell tumor in a cryptorchid Schnauzer dog, highlighting the need to evaluate sex development disorders during testicular...

Persistent Müllerian Duct Syndrome Associated with a Sertoli Cell Tumor in a Male Schnauzer Dog

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Cite This Study

Persistent Müllerian Duct Syndrome Associated with a Sertoli Cell Tumor in a Male Schnauzer Dog

Discussion

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Implication

Key Points

Cite This Study

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