The concentrations of dopamine and noradrenaline were determined in some limbic, cortical, striatal and mesencephalic regions of 12 humans. The highest concentrations of dopamine were found in the neostriatum and in the nucleus accumbens. Lower but significant values were detected in the globus pallidus, the substantia perforata anterior, the substantia nigra and in the region medial to the substantia nigra (area A 10). The concentrations of noradrenaline were generally low with the highest values in the area A 10 and the substantia perforata anterior.
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Nyberg et al. (1982) studied this question.
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