Answers are grounded in this paper and cite their sources.
(+)-Lentiginosine (14) and (7R)-7-hydroxylentiginosine (26), powerful inhibitors of amyloglucosidases, and their enantiomers were obtained in high overall yields by a multistep synthesis involving 1,3-dipolar cycloaddition of enantiopure tartaric acid derived pyrroline N-oxides. Structurally related (S,S)-3,4-dihydroxypyrrolidines 29-33 were synthesized as simpler models and tested towards 24 glycosidases.
No takes yet. Share an insight, caveat, or question.
Cardona et al. (2000) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: