Why the study?
Does an implanted radiofrequency coil improve MRI signal-to-noise ratio and motion artifact suppression in rats with spinal cord injury compared to an external surface coil?
Does an implanted radiofrequency coil improve MRI signal-to-noise ratio and motion artifact suppression in rats with spinal cord injury compared to an external surface coil?
An implanted radiofrequency coil enables high-resolution in vivo MRI of rat spinal cord injury with superior signal-to-noise ratio and reduced motion artifacts.
Enables high-resolution rodent spinal cord MRI; leaves open translation to clinical use.
We have developed an implanted radiofrequency coil to obtain high resolution in vivo MR images at 1.9 Tesla of rat spinal cords that have been injured using a standardized weight drop technique. The signal-to-noise ratio and motion artifact suppression of these images is superior to that achieved in earlier attempts at this field strength using an external surface coil. The high quality and spatial resolution provided by this technique afford the possibility for longitudinal studies of experimental spinal cord injury before and after treatment, as well as detailed correlation of in vivo MRI contrast, histopathological findings, and functional deficit, in a controlled setting.
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Ford et al. (1994) studied this question.
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