Association of clinical features and metabolic disorders with behavioral and psychological factors in residents of the Tver region

Objective. To assess the relationship of behavioral and psychological factors with clinical features and metabolic disorders in residents of the Tver region. Material and methods. The protocols of 480 subjects were studied: 146 males and 334 females aged 45 to 60. All respondents were divided into three groups: Group 1 included 107 subjects (22 males and 85 females) with normal body weight (body mass index (BMI) 23.1±1.33 kg/m2, mean age 52.3±6.6 years); Group 2 included 195 subjects (71 males and 124 females) with overweight (BMI 27.7±1.38 kg/m2, mean age 56.8±6.3 years); Group 3 included 178 subjects (53 males and 125 females) with alimentary-constitutional obesity (BMI 33.6±1.2 kg/m2, mean age 50.8±5.8 years). All subjects underwent a general clinical examination with anthropometric measurements, laboratory studies, and questionnaires regarding chronic non-communicable diseases (CNCDs) and lifestyle features, including physical activity, bad habits, and psychological status. Results. More than 30% of study patients have an abdominal type of ACO, mainly grade I, and concomitant hypertension, also mainly grade I; the prevalence of hypertension increases with obesity (42%). Significantly more often, other CNCDs were also noted: cardiovascular diseases, asthma, type 2 diabetes mellitus (T2DM), and dyslipidemia. Conclusion. Lipid and carbohydrate metabolism disorders and an increase in C-reactive protein were more common in individuals with obesity. Females with excess body weight were the most physically active. Smoking and alcohol consumption were more common in obese and overweight males and overweight females. High stress levels were more common in females without a clear correlation with the body mass index.