Population
Arterial casts from the brain of an autopsy case of a 17-year-old non-hypertensive male (n=1)
Design
Preclinical
Authors
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Should not change clinical models of cerebral autoregulation; leaves open large-artery contributions to basal ganglia hypertensive injury.
Mathematical analysis of cerebral arterial casts reveals that large arterial branches account for a significant pressure drop, with unique hemodynamic patterns in the basal ganglia potentially explaining their predisposition to hypertensive injuries.
Hitoshi Fukasawa (1969) studied this question.
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