April 1, 1987AJP Heart and Circulatory Physiology

Segmental vascular responses to acute hypertension in cerebrum and brain stem

View Full Paper

Ask AI

Bookmark

Population

Anesthetized cats

Comparison

Acute hypertension vs Control conditions

Design

Preclinical

Authors

FFFrank M. FaraciVascular Medicine WMWilliam G. MayhanUniversity of Nebraska at Omaha DHDonald D. HeistadOregon National Primate Research Center

Discussion

Member takes

Implication

Differential autoregulation may inform regional brain vulnerability in hypertension; hypothesis-generating and requires human validation before clinical relevance.

Structured PICO

Population

Anesthetized cats

Intervention

Acute hypertension (moderate and severe elevation of aortic pressure)

Comparator

Control conditions

Outcome

Blood flow, pressure in pial arteries, and resistance of large and small vessels in cerebrum and brain stemsurrogate

More effective autoregulation in the brain stem compared to the cerebrum during severe hypertension is driven by greater resistance of small vessels.

Cite This Study

Faraci et al. (1987) studied this question.

synapsesocial.com/papers/6a77cb2a576efb0ddaf7a179 https://doi.org/10.1152/ajpheart.1987.252.4.h738

Topics

Hypertension management

View Full Paper

Ask AI

Bookmark

Implication

Differential autoregulation may inform regional brain vulnerability in hypertension; hypothesis-generating and requires human validation before clinical relevance.

Segmental vascular responses to acute hypertension in cerebrum and brain stem

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Segmental vascular responses to acute hypertension in cerebrum and brain stem

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider