Key result
Percutaneous closure of a post-myocardial infarction ventricular septal defect using a trans-septal approach was successfully performed in an 80-year-old high-risk male, resulting in hemodynamic stability and discharge on post-procedure day 5.
Why the study?
Post-myocardial infarction ventricular septal defect carries high morbidity and surgical mortality, prompting the exploration of percutaneous alternatives in patients with elevated surgical risk.
Case Report (n=1)
No
Trans-septal percutaneous closure of post-MI VSD is a feasible, minimally invasive, and potentially life-saving alternative to surgical repair in patients with prohibitive surgical risk.
May support transseptal percutaneous closure in high-risk elderly patients; hypothesis-generating and should not change practice.
Ventricular septal defect (VSD) following myocardial infarction (MI) is a rare but life-threatening complication associated with high morbidity and mortality. While surgical repair remains the standard of care, its high mortality risk has prompted the exploration of percutaneous alternatives, especially in patients with elevated surgical risk. This case report describes the successful percutaneous closure of a post-MI VSD via a trans-septal approach in an 80-year-old male, highlighting its feasibility, safety, and favorable clinical outcome in a high-risk patient.
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Karki et al. (2025) conducted a case report in Post-myocardial infarction ventricular septal defect (n=1). Percutaneous VSD closure via trans-septal approach was evaluated on Successful closure of VSD and hemodynamic stability. Percutaneous closure of a post-myocardial infarction ventricular septal defect using a trans-septal approach was successfully performed in an 80-year-old high-risk male, resulting in hemodynamic stability and discharge on post-procedure day 5.
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