Vulvovaginal Candidiasis—What We Do and Do Not Know

Editorials1 September 1984Vulvovaginal Candidiasis—What We Do and Do Not KnowJACK D. SOBEL, M.D.JACK D. SOBEL, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-101-3-390 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptMost women who see a physician for gynecologic problems present with vaginal symptoms (1). Candidal vaginitis is the second commonest form of vaginal infection currently seen in the United States, occurring slightly less frequently than nonspecific vaginitis (1).Many women go through life without suffering any episodes of candidal vaginitis. Most, however, have infrequent isolated attacks and respond readily to various topical, intravaginal antifungal agents. A third subpopulation suffers repeated bouts of incapacitating vulvovaginal candidiasis, presenting with attacks almost every month or with chronic intractable symptoms. We do not know the exact size of this last group, but virtually every...References1. Nonreported sexually transmitted diseases. MMWR. 1979;28:61. Google Scholar2. FLEURY F. Adult vaginitis. Clin Obstet Gynecol. 1981;24:407-38. CrossrefMedlineGoogle Scholar3. MILESOLSENROGERS MLA. Recurrent vaginal candidiasis: importance of an intestinal reservoir. JAMA. 1977;238:1836-7. CrossrefMedlineGoogle Scholar4. VILUPILLAITHIN SR. Treatment of vulvovaginal yeast infection with nystatin. Practitioner. 1977;219:897-901. Google Scholar5. MILNEWARNOCK JD. Effect of simultaneous oral and vaginal treatment on the rate of cure and relapse in vaginal candidosis. Br J Vener Dis. 1979;55:362-5. MedlineGoogle Scholar6. JONESJONES HG. Novak's Textbook of Gynecology. 10th ed. Baltimore: Williams & Wilkins; 1981:266-9. Google Scholar7. WILLSONCARRINGTONLEDGER JEW. Obstetrics and Gynecology. 7th ed. St. Louis: CV. Mosby Co.; 1983:608-9. Google Scholar8. ODDSABBOTT FA. A simple system for the presumptive identification of Candida albicans and differentiation of strains within species. Sabouraudia. 1980;18:301-8. CrossrefMedlineGoogle Scholar9. ODDS F. Genital candidosis. Clin Exp Dermatol. 1982;7:345-54. CrossrefMedlineGoogle Scholar10. ODDS F. Cure and relapse with antifungal therapy. Proc R Soc Med. 1977;70 (suppl 4):24-8. MedlineGoogle Scholar11. GARCIA-TAMAYOCASTILLOMARTINEZ JGA. Human genital candidiasis: histochemistry, scanning and transmission electron microscopy. Acta Cytol (Baltimore). 1982;26:7-14. MedlineGoogle Scholar12. MILSOMFORSSMAN IL. Treatment of vaginal candidosis with a single 500-mg clotrimazole pessary. Br J Vener Dis. 1982;58:124-6. MedlineGoogle Scholar13. ODDS F. Pathogenesis of candidosis. In: ODDS FC, ed. Candida and Candidosis. Baltimore: University Park Press; 1979:189. Google Scholar14. ESCHENBACH D. Vaginal infection. Clin Obstet Gynecol. 1983;26:186-202. CrossrefMedlineGoogle Scholar15. DAVIDSONHAYESHUSSEIN FJS. Recurrent genital candidosis and iron metabolism. Br J Vener Dis. 1977;53:123-5. MedlineGoogle Scholar16. DAVIDSONMOULD FR. Recurrent genital candidosis in women and the effect of intermittent prophylactic treatment. Br J Vener Dis. 1978;54:176-83. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. 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