Key result
A wearable light reflection rheography system achieved diagnostic accuracies of 69-72% for slight simulated DVT and 73-76% for serious simulated DVT.
Why the study?
Deep vein thrombosis can lead to life-threatening pulmonary embolism, motivating the need for early detection systems usable in non-medical settings.
Does a light reflection rheography examination system accurately detect simulated deep vein thrombosis in lower limbs?
Does a light reflection rheography examination system accurately detect simulated deep vein thrombosis in lower limbs?
A novel wearable light reflection rheography system demonstrated moderate accuracy (up to 76%) in detecting simulated deep vein thrombosis, suggesting potential utility as a homecare screening tool.
Supports wearable DVT screening development; leaves open clinical validation and utility.
Deep vein thrombosis (DVT) of lower limbs can easily arise from prolonged sitting or standing. Elders and pregnant women are most likely to have this disease. When the embolus of DVT comes to pass the lung, it will become a life-threatening disease. Thus, for DVT disease, early detection and the early treatment are needed. The goal of this study was to develop an examination system to be used at non-medical places to detect the DVT of lower limbs with light reflection rheography (LRR). Consisting of a wearable device and a mobile application (APP), the system is operated in a wireless manner to control the actions of sensors and display and store the LRR signals on the APP. Then, the recorded LRR signals are processed to find the parameters of DVT examination. Twenty subjects were recruited to perform experiments. The veins of lower limbs were occluded by pressuring the cuff up to 100 mmHg and 150 mmHg to simulate the slight and serious DVT scenarios, respectively. Six characteristic parameters were defined to classify whether there was positive or negative DVT using the receiver operating characteristic curves, including the slopes of emptying and refilling curves in the LRR signal, and the changes of venous pump volume. Under the slight DVT scenario (0 mmHg vs. 100 mmHg), the first three parameters, m10, m40, and m50, had accuracies of 72%, 69%, and 69%, respectively. Under the serious DVT scenario (0 mmHg vs. 150 mmHg), m10, m40, and m50 achieved accuracies of 73%, 76%, and 73%, respectively. The experimental results show that this proposed examination system may be practical as an auxiliary tool to screen DVT in homecare settings.
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Liu et al. (2021) studied Deep vein thrombosis (n=20). Light reflection rheography (LRR) examination system vs. No occlusion (0 mmHg) was evaluated on Accuracy of LRR parameters (m10, m40, m50) to classify DVT. A wearable light reflection rheography system achieved diagnostic accuracies of 69-72% for slight simulated DVT and 73-76% for serious simulated DVT.
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