Key result
Transcatheter pulmonary valve implantation for dysfunctional right ventricular outflow tracts demonstrated a 5-year freedom from reintervention or replacement of 76%.
TPVI is an evolving treatment for dysfunctional RVOT, with 76% 5-year freedom from reintervention, though bacterial endocarditis remains a concern.
Supports transcatheter pulmonary valve implantation as a viable alternative to surgery; leaves open the long-term.
PURPOSE OF REVIEW: Procedural technique and short-term outcomes of transcatheter pulmonary valve implantation (TPVI) have been widely described. The purpose of this article is to provide an update on current valve technology, and to focus on recent data surrounding TPVI in the dilated right ventricular outflow tract (RVOT), hybrid interventions, significant outcomes, and procedural costs. RECENT FINDINGS: Transcatheter valve technology has expanded with current trials evaluating self-expandable valves that can be implanted in dilated RVOTs. Until those valves are widely available, hybrid techniques have been shown to offer a potential alternative in these patients, as well as in patients of small size. Although medium-term results of TPVI have shown 5-year freedom from reintervention or replacement of 76%, new data have underlined some concerns relating to bacterial endocarditis after the procedure. Procedural costs remain a concern, but vary greatly between institutions and healthcare systems. SUMMARY: TPVI has emerged as one of the most innovative procedures in the treatment of patients with dysfunctional RVOT and pulmonary valves. Further device development is likely to expand the procedure to patients of smaller size and with complex, dilated RVOTs.
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Salavitabar et al. (2017) conducted a review in Dysfunctional right ventricular outflow tract (RVOT) and pulmonary valves. Transcatheter pulmonary valve implantation (TPVI) was evaluated on 5-year freedom from reintervention or replacement. Transcatheter pulmonary valve implantation for dysfunctional right ventricular outflow tracts demonstrated a 5-year freedom from reintervention or replacement of 76%.
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