Key result
Applying NCEP ATP III criteria instead of ATP II criteria to patients on statin therapy resulted in a 6.8% decrease in LDL-C goal attainment (from 59.8% to 53.0%).
Why the study?
Does applying NCEP ATP III criteria compared to ATP II criteria reduce the rate of LDL-C goal attainment in managed care enrollees on statin therapy?
Observational (n=1,962)
Does applying NCEP ATP III criteria compared to ATP II criteria reduce the rate of LDL-C goal attainment in managed care enrollees on statin therapy?
Absolute Event Rate: 53% vs 59.8%
Absolute Risk Reduction: 6.8%
The application of the more stringent NCEP ATP III guidelines significantly decreases the proportion of statin-treated patients achieving their LDL-C goals, highlighting the need for intensified lipid-lowering therapy.
No takes yet. Share an insight, caveat, or question.
ATP III criteria were associated with lower LDL-C goal attainment in statin users; hypothesis-generating for intensified therapy needs in managed care.
Quilliam et al. (2004) conducted an observational in Patients treated with statin therapy (n=1,962). NCEP ATP III criteria vs. NCEP ATP II criteria was evaluated on Percentage of participants with most recent LDL-C value below the suggested goal. Applying NCEP ATP III criteria instead of ATP II criteria to patients on statin therapy resulted in a 6.8% decrease in LDL-C goal attainment (from 59.8% to 53.0%).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: