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A new series of compounds thought to have some of the properties of major tranquillizers has recently been synthesized (Archer et al., 1962). One of these, oxypertine (Fig. 1) has been made available to us under its code name, WIN.18, 501. Pharmacological studies have shown oxypertine to have tranquillizing, anti-adrenergic and hypotensive properties (Wylie and Archer, 1962).
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Calwell et al. (1964) studied this question.
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