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In vitro study demonstrates antibacterial and antibiofilm activity of BMAP-27-melittin nanoparticles against Streptococcus mutans, highlighting potential for preventing dental caries.
Background & Objective: as the primary pathogen from subgingival plaques. Methods: The BMAP27-Melittin conjugated peptide was purchased from GenScript Company, USA. Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC), Biofilm Inhibitory Concentration (BIC), and Biofilm Eradication Concentration (BEC) of BMAP27-Melittin-NP were calculated using the microtiter method. Results: =0.032, 0.001, and 0.001, respectively). Conclusion: which can be considered a promising compound to prevent or treat dental caries and eradicate the oral infections.
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Pourahmadi et al. (2022) studied this question.
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