Key result
No-touch and no-pump CABG strategies show similar ~3% in-hospital mortality for unclampable aorta.
Why the study?
The unclampable ascending aorta (UAA) is increasingly encountered during CABG, but preoperative diagnosis is often missed and optimal surgical management is unclear.
Does hypothermic ventricular fibrillation (no-touch technique) compared to beating heart revascularization (no-pump technique) affect mortality and complication rates in CABG patients with unclampable ascending aorta?
Cohort (n=211)
Does hypothermic ventricular fibrillation (no-touch technique) compared to beating heart revascularization (no-pump technique) affect mortality and complication rates in CABG patients with unclampable ascending aorta?
Answers are grounded in this paper and cite their sources.
In CABG patients with unclampable ascending aorta, the no-pump technique reduces perioperative complications compared to the no-touch technique, but at the cost of higher ischemia recurrence.
Background —The unclampable ascending aorta (UAA) is a condition increasingly encountered during CABG procedures. We report our experience with CABG patients with UAA and place particular emphasis on the preoperative diagnosis and surgical management. Methods and Results —UAA was diagnosed in 211 of 4812 consecutive CABG patients (4.3%). On the basis of the chest radiograph, echocardiogram, and coronary angiograph, a preoperative diagnosis was achieved in only 58 patients (27.4%). An age of >70 years, diabetes, smoking, unstable angina, diffuse coronaropathy, and peripheral vasculopathy were all predictors of UAA. Patients were treated with hypothermic ventricular fibrillation (no-touch technique n=129) or beating heart revascularization (no-pump technique n=82) depending on the possibility of founding an arterial cannulation site. The overall in-hospital mortality rate was 2.8% (6 of 211) with no differences between the 2 surgical strategies. The no-touch technique was associated with a greater incidence of neurological complications (stroke and transient ischemic attack), renal insufficiency, and stay in the intensive care unit and hospital. However, at midterm follow-up, more patients of the no-pump group had ischemia recurrence. Conclusions —A preoperative diagnosis of UAA is achievable only in a minority of patients, which highlights the necessity revising the current diagnostic protocols. The use of the no-touch technique is associated with an high perioperative risk but a superior possibility of complete revascularization, whereas adoption of the no-pump strategy ensures a smoother postoperative course at the expense of an higher incidence of ischemia recurrence.
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Gaudino et al. (2000) conducted a cohort in Unclampable ascending aorta in coronary artery bypass grafting (CABG) (n=211). Hypothermic ventricular fibrillation (no-touch technique) vs. Beating heart revascularization (no-pump technique) was evaluated on In-hospital mortality. In CABG patients with an unclampable ascending aorta, the no-touch technique and the no-pump strategy yielded a similar overall in-hospital mortality rate of 2.8%.
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