Why the study?
What are the outcomes of selective termination in multiple gestations?
What are the outcomes of selective termination in multiple gestations?
Selective termination is highly successful in dichorionic pregnancies, with intracardiac potassium chloride injection being the preferred method, but carries a high risk of pregnancy loss in monochorionic pregnancies.
Suggests selective termination may succeed in dichorionic but not monochorionic gestations; leaves open need for larger studies before practice guidance.
Twenty-two selective terminations in multiple gestations were performed by a number of different methods. In 17 dichorionic pregnancies there was a successful delivery in surviving singletons or twins. In five monochorionic pregnancies undergoing selective termination there was a successful delivery in only one and a pregnancy loss in the other four. Six of the 18 delivered pregnancies were complicated by premature labor and delivery. Among the several methods used for selective termination, intracardiac potassium chloride injection appears to be the procedure of choice in dichorionic pregnancies.
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Golbus et al. (1988) studied this question.
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