Population
Outer medullary descending vasa recta dissected from the outer medullary vascular bundles of young rats
Comparison
Bradykinin (BK) at concentrations > 10(-11) M vs Baseline values; selective BK B2-receptor…
Design
Preclinical
Authors
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Provides mechanistic insight into rodent renal microvasculature; leaves open translation to human physiology or disease.
Bradykinin increases endothelial intracellular calcium via the B2 receptor and vasodilates descending vasa recta in a rat model.
Pallone et al. (1998) studied this question.
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