Key result
Selective occlusion of three septal arteries with a pericardium-covered stent completely reduced LVOT gradient and improved NYHA class from III to I in a patient with severe HOCM.
Why the study?
Does selective occlusion of septal arteries with a pericardium-covered stent reduce left ventricular outflow tract gradient in severe hypertrophic obstructive cardiomyopathy?
Does selective occlusion of septal arteries with a pericardium-covered stent reduce left ventricular outflow tract gradient in severe hypertrophic obstructive cardiomyopathy?
Selective occlusion of septal arteries using a pericardium-covered stent can successfully reduce LVOT gradient and improve symptoms in severe hypertrophic obstructive cardiomyopathy.
Answers are grounded in this paper and cite their sources.
May support novel septal occlusion in refractory HOCM; hypothesis-generating and should not change practice without prospective trials.
This report describes a patient with severe hypertrophic obstructive cardiomyopathy in New York Heart Association functional class III. Complete reduction of left ventricular outflow tract gradient was achieved by the selective occlusion of three target septal arteries with a pericardium-covered stent. The patient's in-hospital course was uneventful and has improved to functional class I.
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Gaspar et al. (1999) studied this question. Selective occlusion of three septal arteries with a pericardium-covered stent completely reduced LVOT gradient and improved NYHA class from III to I in a patient with severe HOCM.
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