A pilot study of the relationship between cardiovascular risk and routine mammography data in women

Objective. To assess the relationship between cardiovascular risk and routine mammography data in women aged ≥ 40 years. Material and methods. We retrospectively analyzed mammography data in 538 consecutive patients. Breast density and calcifications were assessed according to the ACR scales, cardiovascular risk — in accordance with the Russian Society of Cardiology guidelines. Statistical analysis was performed using R 4.1 environment. Results. There was a relationship between mammographic parameters and cardiovascular risk in women aged ≥40 years. Low breast density and calcifications were associated with higher cardiovascular risk. Vascular type of calcifications was typical for patients with high and very high cardiovascular risk. The absence of significant differences in breast density and characteristics of calcification between the right and left mammary glands will be considered when forming an integral marker. This will allow verification of results. Conclusion. A method for additional analysis of preventive mammography data may allow assessing the cardiovascular risk and determining rational patient routing at the 2nd stage of screening. Re-classifying the cardiovascular risk downwards will make it possible to avoid unjustified prescription of statins, while reclassifying upwards will facilitate prescription of optimal treatment and additional motivation for women to correct cardiovascular risk factors.