Key result
The PRAGMATIST tool provides a semi-quantitative framework to prioritize foot-and-mouth disease virus antigens for vaccine banks by combining source area risk, lineage distribution, and vaccine coverage.
Why the study?
Optimal selection of distinct foot-and-mouth disease virus antigens in vaccine banks must balance covering risks from unevenly distributed lineages with purchasing and maintenance costs.
PRAGMATIST provides a transparent, evidence-based decision support tool to assist FMD vaccine bank managers in prioritizing vaccine antigens for storage based on regional risk profiles.
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PRAGMATIST aids risk-based prioritization of FMD antigens in banks; leaves open prospective validation before routine adoption.
Ludi et al. (2022) studied Foot-and-mouth disease (n=2,150). PRAGMATIST decision-support tool was evaluated on Vaccine score (VS) for prioritizing FMDV antigens. The PRAGMATIST tool provides a semi-quantitative framework to prioritize foot-and-mouth disease virus antigens for vaccine banks by combining source area risk, lineage distribution, and vaccine coverage.
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